Selected Recent Publications

2018

David Roquis, Aaron Taudt, Kathrin K. Geyer, Gilda Padalino, Karl F. Hoffmann, Nancy Holroyd, Matt Berriman, Benoit Aliaga, Cristian Chaparro, Christoph Grunau, Ronaldo de Carvalho Augusto (2018) ‘Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni’ PLoS Pathogens doi.org/10.1371/journal.ppat.1007066

Duncan, J., Cutress, D., Morphew, R.M., Brophy, P.M. (2018) 'Purification of native Sigma Class Glutathione Transferase from Fasciola hepatica' Mol Biochem Parasitol 27 April 2018 doi: 10.1016/j.molbiopara.2018.04.006

Crusco, A., Bordoni, C., Chakroborty, A., Whatley, K.C.L., Whiteland, H., Westwell, A., Hoffmann, K. (2018) 'Design, synthesis and anthelmintic activity of 7-keto-sempervirol analogues' European Journal of Medicinal Chemistry Vol 152, 25 May 2018, pages 87-100 https://doi.org/10.1016/j.ejmech.2018.04.032

Geyer, K., Munshi, S. E., Vickers, M., Squance, M., Wilkinson, T., Berrar, D., Chaparro, C., Swain, M. & Hoffmann, K. (2018). 'The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulation transcription, translation and stem cell activities' International Journal for Parasitology: Drugs and Drug Resistance, 01 Apr 2018, DOI 10.1016/j.ijpddr.2018.03.006.

2017

Nur-e-Alam, M, Yousaf, M, Ahmed, S, Al-Sheddi, ES, Shah, I, Fazakerley, D, Bari, A, Ghabbour, HA, Threadgill, MD, Whatley, K, Hoffmann, K & Al-Rehaily, AJ 2017, 'Neoclerodane Diterpenoids from Reehal Fatima, Teucrium yemense' Journal of Natural Products. DOI: 10.1021/acs.jnatprod.7b00188

Pierre, S, Griffith, G, Morphew, R, Mur, L & Scott, I 2017, 'Saprotrophic proteomes of biotypes of the witches’ broom pathogen Moniliophthora perniciosa' Fungal Biology. DOI: 10.1016/j.funbio.2017.05.004

Geyer, K, Niazi, U, Duval, D, Cosseau, C, Tomlinson, C, Chalmers, I, Swain, M, Cutress, D, Bickham-Wright, U, Munshi, SE, Grunau, C, Yoshino, TP & Hoffmann, K 2017, 'The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni' PLoS Neglected Tropical Diseases, vol 11, no. 5, e0005246. DOI: 10.1371/journal.pntd.0005246

Adema, CM, Hillier, LW, Jones, CS, Loker, ES, Knight, M, Minx, P, Oliveira, G, Raghavan, N, Shedlock, A, do Amaral, LR, Arican-Goktas, HD, Assis, JG, Baba, EH, Baron, OL, Bayne, CJ, Bickham-Wright, U, Biggar, KK, Blouin, M, Bonning, BC, Botka, C, Bridger, JM, Buckley, KM, Buddenborg, SK, Lima Caldeira, R, Carleton, J, Carvalho, OS, Castillo, MG, Chalmers, IW, Christensens, M, Clifton, S, Cosseau, C, Coustau, C, Cripps, RM, Cuesta-Astroz, Y, Cummins, SF, Di Stephano, L, Dinguirard, N, Duval, D, Emrich, S, Feschotte, C, Feyereisen, R, Fitzgerald, P, Fronick, C, Fulton, L, Galinier, R, Gava, SG, Geusz, M, Geyer, KK, Giraldo-Calderón, GI, de Souza Gomes, M, Gordy, MA, Gourbal, B, Grunau, C, Hanington, PC, Hoffmann, KF, Hughes, D, Humphries, J, Jackson, DJ, Jannotti-Passos, LK, De Jesus Jeremias, W, Jobling, S, Kamel, B, Kapusta, A, Kaur, S, Koene, JM, Kohn, AB, Lawson, D, Lawton, SP, Liang, D, Limpanont, Y, Liu, S, Lockyer, AE, Lovato, TL, Ludolf, F, Magrini, V, Mcmanus, DP, Medina, M, Misra, M, Mitta, G, Mkoji, GM, Montague, MJ, Montelongo, C, Moroz, LL, Munoz-Torres, MC, Niazi, U, Noble, LR, Oliveira, FS, Pais, FS, Papenfuss, AT, Peace, R, Pena, JJ, Pila, EA, Quelais, T, Raney, BJ, Rast, JP, Rollinson, D, Rosse, IC, Rotgans, B, Routledge, EJ, Ryan, KM, Scholte, LLS, Storey, KB, Swain, M, Tennessen, JA, Tomlinson, C, Trujillo, DL, Volpi, EV, Walker, AJ, Wang, T, Wannaporn, I, Warren, WC, Wu, X-J, Yoshino, TP, Yusuf, M, Zhang, S-M, Zhao, M & Wilson, RK 2017, 'Whole genome analysis of a schistosomiasis-transmitting freshwater snail' Nature Communications, vol 8, 15451 (2017), pp. 15451. DOI: 10.1038/ncomms15451

Jones, R, Williams, H, Dalesman, S, Sinmidele, A, Thomas, RK & Brophy, P 2017, 'The prevalence and development of digenean parasites within their intermediate snail host, Galba truncatula, in a geographic area where the presence of Calicophoron daubneyi has recently been confirmed' Veterinary Parasitology. DOI: 10.1016/j.vetpar.2017.03.021

Garcia-Perez, I, Posma, JM, Gibson, R, Chambers, ES, Hanson, TH, Vestergaard, H, Hansen, T, Beckmann, M, Pedersen, O, Elliott, P, Stamler, J, Nicholson, JK, Draper, J, Mathers, JC, Holmes, E & Frost, G 2017, 'Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial' Lancet Diabetes and Endocrinology, vol 5, no. 3, pp. 184-195. DOI: 10.1016/S2213-8587(16)30419-3

2016

Cosseau, C, Wolkenhauer, O, Padalino, G, Geyer, K, Hoffmann, K & Grunau, C 2016, '(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach' Trends in Parasitology. DOI: 10.1016/j.pt.2016.12.002

Damas, J, O'connor, R, Farré, M, Lenis, V, Martell, H, Mandawala, A, Fowler, K, Joseph, S, Swain, M, Griffin, D & Larkin, DM 2016, 'Upgrading short read animal genome assemblies to chromosome level using comparative genomics and a universal probe set' Genome Research, vol 27, pp. 875-884. DOI: 10.1101/gr.213660.116

Özkan, Ş, Vitali, A, Lacetera, N, Amon, B, Bannink, A, Bartley, DJ, Blanco-penedo, I, De Haas, Y, Dufrasne, I, Elliott, J, Eory, V, Fox, NJ, Garnsworthy, PC, Gengler, N, Hammami, H, Kyriazakis, I, Leclère, D, Lessire, F, Macleod, M, Robinson, TP, Ruete, A, Sandars, DL, Shrestha, S, Stott, AW, Twardy, S, Vanrobays, M-L, Ahmadi, BV, Weindl, I, Wheelhouse, N, Williams, AG, Williams, HW, Wilson, AJ, Østergaard, S & Kipling, RP 2016, 'Challenges and priorities for modelling livestock health and pathogens in the context of climate change' Environmental Research, vol 151, pp. 130-144. DOI: 10.1016/j.envres.2016.07.033

Kara, A, Vickers, M, Swain, M, Whitworth, D & Fernandez-Fuentes, N 2016, 'MetaPred2CS: a sequence-based meta-predictor for protein-protein interactions of prokaryotic two-component system proteins' Bioinformatics, vol 32, no. 21, pp. 3339-3341. DOI: 10.1093/bioinformatics/btw403

Jones, R, Brophy, P, Mitchell, ES & Williams, H 2016, 'Rumen fluke Calicophoron daubneyi on Welsh farms: Prevalence, risk factors, and observations on co-infection with Fasciola hepatica' Parasitology, pp. 237-247. DOI: 10.1017/S0031182016001797

Mizeranschi, AE, Swain, MT, Scona, R, Fazilleau, Q, Bosak, B, Piontek, T, Kopta, P, Thompson, P & Dubitzky, W 2016, 'MultiGrain/MAPPER: A distributed multiscale computing approach to modeling and simulating gene regulation networks' Future Generation Computer Systems, vol 63, pp. 1-14. DOI: 10.1016/j.future.2016.04.002

Kock, R, Chardonnet, P & Risley, C 2016, Antelope Diseases - the Good, the Bad and the Ugly. in Antelope Conservation: From Diagnosis to Action. Conservation Science and Practice, Wiley, pp. 108-135.

Morphew, R, Wilkinson, T, MacKintosh, N, Jahndel, V, Paterson, S, McVeigh, P, Abbas Abidi, SM, Saifullah, K, Raman, M, Ravikumar , G, LaCourse, EJ, Maule, AG & Brophy, P 2016, 'Exploring and Expanding the Fatty-Acid-Binding Protein Superfamily in Fasciola Species' Journal of Proteome Research, vol 15, no. 9, pp. 3308-3321. DOI: 10.1021/acs.jproteome.6b00331

Niazi, U, Geyer, K, Vickers, M, Hoffmann, K & Swain, M, DISMISS: MeDIP-seq: High-throughput sequencing, 2016, Software, OMICtools.

Niazi, U, Geyer, KK, Vickers, MJ, Hoffmann, K & Swain, M 2016, 'DISMISS: detection of stranded methylation in MeDIP-Seq data' BMC Bioinformatics, vol 17, 295. DOI: 10.1186/s12859-016-1158-7

Poglayen, D, Marín-López, MA, Bonet, J, Fornes, O, Garcia-Garcia, J, Planas-Iglesias, J, Segura, J, Oliva, B & Fernandez-Fuentes, N 2016, 'InteractoMIX: a suite of computational tools to exploit interactomes in biological and clinical research' Biochemical Society Transactions, vol 44, no. 3, pp. 917-924. DOI: 10.1042/BST20150001

Hart, E, Onime, LA, Davies, T, Morphew, R & Kingston-Smith, A 2016, 'The effects of PPO activity on the proteome of ingested red clover and implications for improving the nutrition of grazing cattle' Journal of Proteomics, vol 141, pp. 67-76. DOI: 10.1016/j.jprot.2016.04.023

McCammick, E, McVeigh, P, McCusker, P, Timson, D, Morphew, R, Brophy, P, Marks, N, Mousley, A & Maule, A 2016, 'Calmodulin disruption impacts growth and motility in juvenile liver fluke' Parasites & Vectors, vol 9, 46. DOI: 10.1186/s13071-016-1324-9